Determination of the protective effects resulting from the use of filters enclosing biomaterials (SPIN) on the oxidative stress damage in the animal central nervous system and electromagnetic radiation exposure.
In recent years there has been extensive controversy over the biological effects of electromagnetic radiation (EMR ) and its consequences on health. Emerging experimental data indicates that EMR, such as that produced by GSM 900MHz mobile phones, have a significant impact on cell biology and ultimately on human health for being capable of increasing the presence of free radicals, with consequent induction of oxidative stress and possible damage on major organic constituents of the cell, such as proteins, lipids and nucleic acids.
State-of-the-art features reveal the damage in rat’s brain cells by subjecting it to electromagnetic field (EMR) exposure for differing lengths of time (12 and 24 hours) at head level, a phenomenon similar to the use of mobile phones (900 MHz - 4Wkg SAR-1).
Cell damage, expressed as oxidative damage of brain proteins, has been quantitatively assessed by different parameters, all representing the index of intensity as:
- carbonyl groups (DPNH)
- hydroxynonenal (HNE)
- SH-groups (HS).
To have a fair indication of uniformity and extent of the harm done, the quantitative parameters were evaluated in different tissues of the central nervous system (cortex, hippocampus, striatum, cerebellum).
The experiment consisted of :
groups of rats that were thusly treated:
- a CHECK group not exposed to electromagnetic fields
- two groups exposed to electromagnetic fields, for 12 and 24 hours respectively
- two groups exposed to same electromagnetic fields and for the same time but with interposition, between the electromagnetic source and the animal cage, of a protective barrier formed by the product in question (Spin).
Results:
1. Extent of cellular damage:
Under these experimental conditions of electromagnetic stress, cell damage is statistically significant compared to CHECK group (p <0.05). The extent of damage is directly proportional to the time of exposure.
2 . Degree of protection
Cell damage is prevented to a statistically significant degree (greater than 95% protection) by interposition of the "Spin barrier" between the source of the electromagnetic field and the animal.
The degree of protection is virtually absolute, as evidenced by the superposition of HNE and DPHN values found at various tissues’ levels of CHECK animals (not exposed to EMR) and animals exposed to EMR in presence of "SPIN."
Protection is also maximal in case of a longer exposure time (24 h).
